Anywhere But Sacramento?

Freeway entrance designating San Francisco for I-5 in Stockton, California

Both of California's largest metro areas are represented on this sign mounted on Interstate 5 overlooking Stockton city streets. While San Francisco isn't directly reachable via I-5, it can be reached via I-205, I-580, and I-80. It might be simpler just to go to Sacramento and work your way over via I-80 (but it would probably take longer).