Missouri 759, the Stockyards Expressway in St. Joseph, is a divided route that starts just north of a Burlington Northern-Santa Fe railroad spur that crosses the roadway just south of the route's intersection with Lower Lake Road. There's no END marker going southbound; northbound, here's the first sign that you're on Missouri 759. The road continues southward from here as a city street eventually connecting with Route U, a few hundred feet from its intersection with Missouri 752 and US 59.