Photo courtesy of David Backlin (taken July 2007)
Interstate 180 in Cheyenne, Wyoming is actually not a freeway, but it still carries an Interstate designation. Perhaps symbolically, David Backlin found that it was marked with smaller-than-usual markers, along with Business Loop 25, US 85, and Business US 87. From this distance, it appears in the photo that the US 85 and US 87 markers are of normal size, but David has indicated that they are small, too.